Research progress on Cornus officinalis and its active compounds in the treatment of diabetic nephropathy

Diabetic nephropathy (DN) is a kidney disorder secondary to diabetes and one of the main diabetic microvascular complications. As number patients grows, DN has become leading cause chronic disease in China. Unfortunately, no definitive cure currently exists for DN. Cornus officinalis (CO), frequently utilized clinical settings mellitus treatment, proven vital both preventing treating This article explores pathogenesis how CO its active compounds regulate glucose lipid metabolism, exhibit anti-inflammatory properties, inhibit oxidative stress, podocytes, manage autophagy. The mechanism role treatment are discussed.